It was her concert that was targeted by a suicide bomber in May.
Council leader Sir Richard Leese put forward the motion, describing Grande as "a young American woman for whom it would have been understandable if she never wanted to see this place again".
The honour was bestowed on the 23-year-old following the One Lover Manchester concert which raised funds for the victims of the May 22 terror attack.
He also spoke of the proposed first recipient of the award, Ariana Grande, who had "brought comfort to thousands" when she had returned to the city to perform a benefit concert for those affected by the attack. Instead she, an artist, a performer, was determined that she would not perform again until she had returned to Manchester to perform.
Ariana Grande is now officially an honorary citizen of Manchester, England.
The We Love Manchester Emergency Fund has so far raised over £10 million; £2 million came directly from the One Love Manchester gig which Grande organised with the help of her manager Scooter Braun and friends and family, incluidng Miley Cyrus, Coldplay, and Katy Perry.
Other council officials in the northwest English city voted Wednesday to back the proposal.
The Manchester City Council announced plans to make Ariana an honorary citizen last month, and now the move has been approved by an honorary council, E!
Lorraine Hulme, a ward sister at Wythenshawe Hospital who was on duty on the night of the atrocity, told the meeting: "I feel extremely proud to be part of such an outstanding team and I know the same can be said for all hospitals and their staff involved across the region". But we reckon you've still got a bit to do before you can stand alongside Jack Duckworth, Shaun Ryder or Michelle Keegan as a true child of Manchester.