Constand says Cosby drugged and molested her as she lay helpless on his couch at his nearby home.
"I went upstairs and into my pack, broke one in half and took another half and brought them down and said to her 'Your friends, I have three friends for you to make you relax, '" Cosby said. It was read to them by the judge.
Bill Cosby walks from the Montgomery County Courthouse after jurors in Cosby's sexual assault trial ended first day deliberations without reaching a verdict in Norristown, Pa., Monday, June 12, 2017.
If convicted, he faces up to 30 years in prison.
Steele said the key facts were not contested during the trial, and have remained consistent in Constand's various statements over time: Cosby got to know her and became a mentor; one night in 2004 he gave her pills at his Cheltenham home and they had a sexual encounter.
The arguments came after the defense on Monday called just a single witness at the start of the second week of the trial.
McMonagle defended the good faith of his client, saying Cosby had agreed to speak at length to investigators in 2005 when he could have kept silent, and rounded on the press.
Andrea Constand says she was drugged and molested. "It's criminal", the district attorney Kevin Steele said.
That meant the prosecution rested its case on Friday, just five days after the trial began.
Cosby did not take the stand, ending days of suspense over whether the jury would hear directly from him.
The 79-year-old comedian is charged with three counts of aggravated indecent assault. They complained that prosecutors were improperly striking blacks from the jury chosen in Pittsburgh. Constand also attended the closing arguments, and showed little reaction.
He pointed out that Constand telephoned Cosby dozens of times after the alleged assault.
"This isn't talking to a trustee". His lawyer has said they were lovers sharing a consensual sexual encounter.
"Just tell the truth - what are we doing here?" he continued, one of many exclamations he made in a fiery and at times histrionic closing that lasted almost two hours.
Camille Cosby - the entertainer's wife of more than 50 years - drew stares because she was in the courthouse after a week of conspicuous absence.
Constand didn't react to McMonagle's closing but smiled at the end of it. Testifying for more than seven hours last week, Constand denied there was any romance between them and told jurors she had rebuffed his advances before the assault.
Prosecutors wanted 13 other accusers to testify at the trial, but the judge allowed just one, an assistant to his agent at the William Morris Agency. His deposition was sealed for years until a judge released parts in 2015 at the request of The Associated Press, prompting a new set of prosecutors to take a fresh look at the case. "This is not a civil case about money, money, money". Constand - then an athletic, 6-foot-tall college basketball staffer - said they made her dazed and groggy, and unable to say no or fight back when Cosby went inside her trousers.
He added: "All the fancy lawyering you have can't get you around your own words".
The jury also heard quotes during the trial from Cosby's deposition about his use of Quaaludes in the 1970s.
Constand said she was "mistaken" when she made those statements to police.
"There are some things in this case that should be fuzzy. Why?" Constand, wearing a casual lightweight blue blazer, was joined by her mother, Gianna Constand, who was a key prosecution witness.
Cosby leaned forward in his chair for most of the defense's closing, occasionally reacting with small nods.
Steele attempted to focus attention back on the trial's central accuser, Andrea Constand, calling her a victim who showed great courage and withstood hours of questioning on the witness stand. Prosecutors have suggested he drugged her with something stronger - perhaps quaaludes.
The defense's solitary witness was Richard Schaeffer, a detective who helped take down Constand's original statement in 2005, a year after the incident.
Schaffer testified this time that Constand had visited with Cosby at an out-of-state casino before the alleged attack and that police knew he had vision problems more than a decade ago. But experts said the legal risks would be conservable. In his statement to police, Cosby says he gave Constand Benadryl after she complained of tension and trouble sleeping, and describes the sexual act that followed as consensual.