Cosby's spokesman, Andrew Wyatt, told reporters outside the courthouse that the jurors understand "the facts of this case don't add up". "If after further deliberations, you are still deadlocked on some or all the charges, you should report that to me".
Cosby has pleaded not guilty to the charges - insisting their sexual contact was consensual - and has denied similar allegations from more than 60 women.
The jurors informed the judge on Thursday morning they were unable to reach a consensus on any of the charges, each of which carries a maximum 10-year prison sentence.
After three days and 28 hours of debate, the group had asked to revisit almost every critical piece of evidence from the trial that began almost two weeks ago - ranging from Cosby's 2005 deposition and police statement, in which he denied drugging and molesting the case's central accuser, Andrea Constand, to Constand's own recollections of the 2004 night she said he attacked her.
The Cosby jury has given no insight to the judge as to the cause of their impasse. "I came home to my boyfriend at the time-who has been my husband, my one and only since 1990-I came home drugged and sexually assaulted by Bill Cosby to him".
Jurors had six questions in the first three days of deliberations, but none on Thursday. The evidence is overwhelmingly in Mr. Cosby's favor.
Cosby, who smiled as it was announced the jury was deadlocked, was ushered out of the courtroom and into a back room, where Wyatt said he's "resting" after calling his wife of 53 years, Camille. She read a prayer before telling Cosby's supporters what she says he did to her. If the panel can't break the deadlock, the judge could declare a hung jury and a mistrial.
A partial verdict of guilt on any of these charges could mean that the prosecution may or may not opt to retry the remaining charges.
University of Pennsylvania law professor David Rudovsky, a criminal lawyer in Philadelphia, said Thursday that the jurors' inability to agree on a verdict didn't surprise him, given the nature of a case that boiled down to Cosby's word against his accuser's and the legal meaning of consent.
The trial began on June 5, and the jury began deliberating Monday evening.
The full context of the portion of Cosby's decade-old testimony in which he said he told Constand the pills he gave her, before their 2004 sexual encounter, were "friends".
The jurors then asked to hear Constand's testimony again Wednesday; indicating that some members of the jury are trying to show the other jurors how inconsistent Constand's statements have been, bringing reasonable doubt.
As deliberations in Bill Cosby's sexual assault trial continue into a fourth day, nerves are frayed, patience is shot and no one is certain when it will all end.
A judge in Pennsylvania has ordered them to resume their consideration of Andrea Constand's sexual assault accusations against the entertainer.